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Neutrogena Stubborn Acne® AM Treatment

Neutrogena Stubborn Acne® AM Treatment

Clinically proven low-dose 2.5% benzoyl peroxide delivers consistent full-face treatment and helps prevent stubborn acne without overdrying or stinging.

Superior aesthetics and high tolerability promote daily use for results that last

  • Vanishes instantly into the skin and dries clear
  • Allows for application under a daily moisturizer or cosmetics
  • Fragrance-free; no burning/stinging or excessive dryness in the vast majority of patients1

The dynamic duo—your patients’ new AM/PM regimen

  • For best results, use them together—Neutrogena Stubborn Acne™ AM Treatment and Neutrogena Stubborn Marks™ PM Treatment
  • The retinol SA (sustained action) patented ingredient in Neutrogena Stubborn Marks™ PM Treatment visibly reduces post-acne marks
  • Learn more about the effective AM/PM Treatment regimen
Active ingredient
Benzoyl Peroxide (2.5%)
Acne Medication


For the treatment of acne.


For external use only.

When using this product

  • Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time

Do not use if you

  • Have very sensitive skin.
  • Are sensitive to benzoyl peroxide.

When using this product

  • Avoid unnecessary sun exposure and use a sunscreen.
  • Avoid contact with the eyes, lips, and mouth.
  • Avoid contact with hair or dyed fabrics, which may be bleached by this product.
  • Skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.

Stop use and ask a doctor if

  • Irritation becomes severe.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away


  • Clean the skin thoroughly before applying this product.
  • Cover the entire affected area with a thin layer one to three times daily.
  • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor.
  • If bothersome dryness or peeling occurs, reduce application to once a day or every other day.
  • If going outside, apply sunscreen after using the product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

Other information

Store at 20ºC to 25ºC (68ºF – 77ºF)

Inactive ingredients

Water, Carbomer homopolymer type B, Ethylhexylglycerin, Sodium hydroxide, Chlorphenesin, Disodium EDTA, Laureth-4, Hydroxypropyl methylcellulose


Call toll-free 1-800-582-4048 or 215-273-8755 (collect) or visit